Revealed: How Male and Female Brain Cells Differ in Gene Activity: Variations in gene expression could help to explain why brain-disease risks differ according to sex. (Miryam Naddaf, 4/17/26, Nature)
[T]he study also identified 3,382 genes that showed sex-biased expression in at least one of the six brain regions. A closer look at these genes revealed a set of 133 genes with consistent sex differences in their average expression levels across all cell types and all regions studied. “That’s very much a ground zero for the molecular effects of sex,” says study co-author Armin Raznahan, a child and adolescent psychiatrist also at the National Institute of Mental Health.