February 26, 2007

CHEER UP, CHARLY:

Retarded mice get smarter with drug: Down syndrome researchers see promise in PTZ, or pentylenetetrazole (Denise Gellene, February 26, 2007, LA Times)

Lab mice with the mental retardation of Down syndrome got smarter after being fed a drug that strengthened brain circuits involved in learning and memory, researchers reported Sunday.

After receiving once-daily doses of pentylenetetrazole, or PTZ, for 17 days, the mice could recognize objects and navigate mazes as well as normal mice did, researchers said. The improvements lasted up to two months after the drug was discontinued, according to the report in the journal Nature Neuroscience.

Scientists said the study opened a promising avenue for research in a field that had seen little success.

Posted by Orrin Judd at February 26, 2007 7:38 AM
Comments

Punctuation!" is (((fun!!!!

Posted by: charly at February 26, 2007 9:58 AM

Wow. A drug whose side effect is to lower the number of votes for the Dems!

Posted by: Raoul Ortega at February 26, 2007 10:54 AM

Too bad they found no effect on normal mice.

Posted by: PapayaSF at February 26, 2007 12:38 PM

This is an outrage. Obviously these researchers did not provide the mouse mothers with amnios so they could make responsible decisions informed by the knowledge of the terrible genetic flaws in their offspring, who never, ever should have been born, since they are just dead weight in mouse society.

Posted by: b at February 26, 2007 2:30 PM

So there's hope for Sawx fans after all?

Posted by: Jim in Chicago at February 26, 2007 11:45 PM
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