May 23, 2006

FOOD, SOAP & PRAYER (via Tom Morin):

Medical Guesswork: From heart surgery to prostate care, the health industry knows little about which common treatments really work (John Carey, 5/29/06, Business Week)

The signs at the meeting were not propitious. Half the board members of Kaiser Permanente's Care Management Institute left before Dr. David Eddy finally got the 10 minutes he had pleaded for. But the message Eddy delivered was riveting. With a groundbreaking computer simulation, Eddy showed that the conventional approach to treating diabetes did little to prevent the heart attacks and strokes that are complications of the disease. In contrast, a simple regimen of aspirin and generic drugs to lower blood pressure and cholesterol sent the rate of such incidents plunging. The payoff: healthier lives and hundreds of millions in savings. "I told them: 'This is as good as it gets to improve care and lower costs, which doesn't happen often in medicine,"' Eddy recalls. "'If you don't implement this,' I said, 'you might as well close up shop."'

The message got through. Three years later, Kaiser is in the midst of a major initiative to change the treatment of the diabetics in its care. "We're trying to put nearly a million people on these drugs," says Dr. Paul Wallace, senior adviser to the Care Management Institute. The early results: The strategy is indeed improving care and cutting costs, just as Eddy's model predicted.

For Eddy, this is one small step toward solving the thorniest riddle in medicine -- a dark secret he has spent his career exposing. "The problem is that we don't know what we are doing," he says. Even today, with a high-tech health-care system that costs the nation $2 trillion a year, there is little or no evidence that many widely used treatments and procedures actually work better than various cheaper alternatives.

This judgment pertains to a shocking number of conditions or diseases, from cardiovascular woes to back pain to prostate cancer. During his long and controversial career proving that the practice of medicine is more guesswork than science, Eddy has repeatedly punctured cherished physician myths. He showed, for instance, that the annual chest X-ray was worthless, over the objections of doctors who made money off the regular visit. He proved that doctors had little clue about the success rate of procedures such as surgery for enlarged prostates. He traced one common practice -- preventing women from giving birth vaginally if they had previously had a cesarean -- to the recommendation of one lone doctor. Indeed, when he began taking on medicine's sacred cows, Eddy liked to cite a figure that only 15% of what doctors did was backed by hard evidence.

A great many doctors and health-care quality experts have come to endorse Eddy's critique. And while there has been progress in recent years, most of these physicians say the portion of medicine that has been proven effective is still outrageously low -- in the range of 20% to 25%. "We don't have the evidence [that treatments work], and we are not investing very much in getting the evidence," says Dr. Stephen C. Schoenbaum, executive vice-president of the Commonwealth Fund and former president of Harvard Pilgrim Health Care Inc. "Clearly, there is a lot in medicine we don't have definitive answers to," adds Dr. I. Steven Udvarhelyi, senior vice-president and chief medical officer at Pennsylvania's Independence Blue Cross.


The only significant health care advances we've made are better nutrition and hygiene.

Posted by Orrin Judd at May 23, 2006 4:10 PM
Comments

The only significant health care advances we've made are better nutrition and hygiene.

Take two and call the doctor in the morning... and get charged $50 for the walk-in visit.

Posted by: Jay at May 23, 2006 4:26 PM

We got a speech from the obstretrician about four years ago that went something like:

'In the fifties, we told pregnant women to do , and that was terrible. Then in the sixties, we told them , which was nearly as wrong; in the 70s, it was , which was madness; in the 80s and 90s it was , which wasn't really right either.

Now, *here's* what you need to do:'

This last bit was given with a perfectly straight face, and I was only just able to keep from bursting into laughter.

Posted by: Mike Earl at May 23, 2006 4:31 PM

Check this one out:
http://www.guardian.co.uk/medicine/story/0,,1781002,00.html

Anyone who claims that we know the first thing about how the brain works is full of it.

Posted by: b at May 23, 2006 4:53 PM

The only significant health care advances we've made are better nutrition and hygiene.

That is nonsense that I'll bet you don't really believe, and that I'll go double or nothing that you don't act upon.

Posted by: Brandon at May 23, 2006 5:22 PM

What did you just lose?

Posted by: oj at May 23, 2006 5:27 PM

I would add vaccinations to that list. Some diseases like cholera and typhus are eliminated by proper hygiene, but many others aren't.

I know what you mean when you say "significant", but I think to say so overlooks a whole host of advances that don't necessarily cross the threshhold of world changing. Dentistry comes to mind. And from my personal experience, I suffered a terrible leg injury that would have left me lame in any other day and age, and thanks to the miracle of surgery, I can walk normally.

Posted by: Dreadnought at May 23, 2006 5:29 PM

John Adams received innoculations.

Posted by: oj at May 23, 2006 5:35 PM

Anti-biotics.

Blood transfusions.

Effective anesthesia.

Insulin.

Cataract surgery.

Kidney transplants.

And so on. Sure, there is a lot that gets forgotten, and the simple things still work best. But, not all that is new is suspect (or insignificant).

Posted by: jim hamlen at May 23, 2006 5:59 PM

You youngun's don't remember the scourge of polio. Pneumonia and yellow fever were almost always fatal, not to mention tetanus and other infections.

Nutrition and hygiene are crucial as the first line of defense, but other life savings inventions have made our lives immeasurably better.

Posted by: erp at May 23, 2006 6:43 PM

That's just counterfactual.

Posted by: oj at May 23, 2006 7:20 PM

But Orrin's basic point is surely valid, even if he forgot antibiotics. Since hygiene, antibiotics and antiseptics it is very hard to know what general advances are due to medicine and what to prosperity. The rest is all very disease specific and not without ambiguity. Erp, did you realize you (and Jim) are still celebrating major advances that are more than half a century old while the medical establishment is feeding us with daily reports of great new advances that keep us beholden to their authority? I'm sorry to be brutal, but at times I have to wonder whether modern medicine (not individual doctors)isn't 90% focussed on extending death more than saving lives.

Posted by: Peter B at May 23, 2006 7:25 PM

I didn't forget antibiotics. They just aren't that significant.

Posted by: oj at May 23, 2006 8:24 PM

They are if you're wounded. Emergency and trauma care have improved significantly even in the last 25 years, thanks to warfare, crime and the automobile. Compare survival rates for seriously wounded soldiers from the Vietnam era to today.

Posted by: joe shropshire at May 23, 2006 9:14 PM

There are too few for it to be significant.

Posted by: oj at May 23, 2006 9:17 PM

Speaking of nutrition and hygiene, lack of them is apparently what caused the Aztecs to be killed off from hemorrhagic fever, while the better nourished and cleaner Spaniards were saved:

http://www.discover.com/issues/feb-06/features/megadeath-in-mexico/?page=1

Posted by: pj at May 23, 2006 11:35 PM

OJ -

Your comment about soldiers and survival rates is perhaps (technically) accurate, but just for soldiers. Don't be obtuse. I suspect what Joe really meant was that the lessons learned in military trauma care have greatly increased the survival rates for all trauma care. As an example, the new materials (based on crustacean shells, I believe) used to provide and promote coagulation for battlefield injuries, are coming into wide use in hospitals.

Peter, I take your point. I did have to think for a few minutes to make my list, and even as I did, I recognized none of it was "new". Some dramatic developments are, such as re-attaching severed limbs, cellular and genetic approaches to fighting cancer, micro-surgery, in-vitro fertilization, surgery in utero, etc. You are probably correct about fending off death, although I don't think that a brutal observation.

However, a clean source of water and lots of anti-bacterial soap would change life in Africa and much of Asia more than any of these developments. That it still hasn't happened 40 or 50 years after the obvious is a pretty brutal statement in itself.

Posted by: jim hamlen at May 24, 2006 12:36 AM

Jim: thanks, but no. I'm pretty sure all the ones who come home who would otherwise not have are significant. Come to think of it, so are the ones who don't.

Posted by: joe shropshire at May 24, 2006 12:53 AM

jim:

Such drastic trauma cases aren't significant.

Posted by: oj at May 24, 2006 7:44 AM

Of course, I realized that the cures I mentioned were 50+ years old, but then nutrition and hygiene are even older.

It depends on your goals whether you think medicine should prolong life (or delay death, if you prefer) or just let nature take its course and allow us to die off when nutrition and hygiene aren't up to the job of fighting off infections or regenerating failing organs.

Here in geezerland, lots of us, men especially, are alive and kicking because of by-pass surgery, diabetics are kept alive with improved methods of monitoring insulin, kidney dialysis and organ transplants are prolonging life as well. Knee and hip replacements are common so we can still get around without assistance and not bother our kids with the tedium of worrying about us.

My 91 year old mother died a couple of weeks ago from vascular dementia aka hardening of the arteries. Not a pretty sight I can tell you. She was perfectly healthy except that her arteries failed to supply blood to her organs and her body quietly closed down until she stopped breathing. For the last couple of months, she was medicated so that she was comfortable and totally out of her mind.

I thank God that she didn't last too long in the state of, as the death certificate said, end stage dementia.

Posted by: erp at May 24, 2006 8:59 AM

Nope. Hips and stuff may improve quality of life for a few folks, but the rest just doesn't have a significant effect.

Posted by: oj at May 24, 2006 9:06 AM

Here's another - the treatment of stomach ulcers has totally changed since 1983, when Australian doctors announced that bacteria actually caused them. After the laughing stopped, and people looked at their work, it was confirmed.

In that vein, the new medicines for acid relief are also a positive development for many people. And some of them are even OTC.

Now remember, just because this stuff gets ad time on TV doesn't mean it is not significant.

Posted by: jim hamlen at May 24, 2006 11:24 AM

Nice if you get tummy aches, but not significant.

Posted by: oj at May 24, 2006 11:49 AM
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