February 17, 2004
25?:
Antibiotics May Raise Risk for Breast Cancer (Rob Stein, February 17, 2004, Washington Post)
Antibiotic use is associated with an increased risk for breast cancer, a new study has found, raising the possibility that women who take the widely used medicines are prone to one of the most feared malignancies. [...]Velicer, Taplin and their colleagues examined computerized pharmacy and cancer screening records of 2,266 women in the Group Health Cooperative, a Seattle area health plan, who developed breast cancer, and 7,953 similar women who did not.
Women who had more than 25 individual prescriptions for antibiotics over an average period of 17 years had twice the risk of breast cancer as those who had taken no antibiotics. The risk was lower for women who took fewer antibiotics, but even those who had between one and 25 prescriptions were about 50 percent more likely to develop breast cancer, the researchers found.
Do you suppose being prescribed antibiotics 1.5 times per year for almost twenty years hints at bigger problems in these women? Posted by Brooke Judd at February 17, 2004 2:59 PM
There in no mention of this "study" on junkscience.com yet but the writer expects the Malloy will eviserate the misuse of the statistics and the confusion of cause and effect.
Posted by: Earl Sutherland at February 17, 2004 4:55 PMThere is nothing on this "study" over on junkscience.com yet, but the writer anticipates that Malloy will eviserate the misuse of statistical analysis and the probable confusion of cause and effect.
Posted by: Earl Sutherland at February 17, 2004 5:00 PMHere's a question: giving antibiotics to cattle fattens them up, so does taking lots of antibiotics make people fatter?
Posted by: PapayaSF at February 17, 2004 5:02 PMDon't you know that correlation equals causation?
Posted by: Michael Gersh at February 17, 2004 6:23 PMThe rest of the story on NPR noted that the correlation could be the result of the chronic conditions that led to the prolonged antibiotic usage, with the antibiotics themselves serving only as a proxy for the true cause.
Posted by: Jeff Guinn at February 17, 2004 9:17 PMI got it as 500 days of use which would be 50 Rx's. or 3 per year.
Posted by: Robert Schwartz at February 17, 2004 10:13 PMCPR is hazardous to your health!!
Persons who survived, following at least 90 seconds of a standard Cardiopulmonary Resuscitation(CPR) procedure, were 40 times more likely to die within the following two years.
ergo: CPR is hazardous to your health!
Posted by: Larry H at February 17, 2004 10:43 PMI know Steve Taplin, and he does not do junk science.
After reading the Post article, it's obvious that most of the above comments were by people who relied only upon the selective extract and misleading comment in this blog.
Either that, or you are idiots.
Posted by: David D at February 18, 2004 2:20 PMI see, David D. Either we agree with you, or we are idiots. That's a great way to win friends and influence people. Dale Carnegie would be proud of you.
Posted by: Michael Gersh at February 18, 2004 8:05 PMI'm not trying to win friends or influence people - I'm saying that if someone bothered to read the article they would have noticed that there was no mention of causation; in fact, it says
" 'One finding that cast doubt on the possibility that antibiotics increase the risk for breast cancer was that the study found the risk for all types of antibiotics', said Debbie Saslow, director of breast and gynecologic cancer for the American Cancer Society. That makes it unlikely it is the antibiotics because different types work in very different ways, she said."
In other words, although breast cancer risk and increased antibiotic use are associated, antibiotic use does not seem to cause breast cancer. Yes, causation seems to be ruled out.
That's why I assumed some posters hadn't read the story.
The reason this study is mentioned anywhere outside of a medical journal is that no one really knows what causes breast cancer. If the same people who get cancer are also at higher risk for bacterial infections, that's an important clue.
To dismiss his "study" as 'junk science' and assume that the epidemiologist is statistically ignorant says to me one of two things: either someone didn't read the article, or they didn't understand it.
In the interests of full disclosure, I applied for a job with Dr Taplin several years ago. He didn't hire me.
Posted by: David D at February 18, 2004 9:23 PMPapayaSF:
Antibiotics allow cattle to be quickly fattened by being fed grain and other quasi-foodstuffs, such as shredded newspaper, without dying.
As cattle's natural diet is grass, not grain, it's necessary if one is determined to fatten them as quickly as possible.
Unless people are being given antibiotics in order to allow them to stomach what otherwise would kill them, it's not similar to a feedlot operation.
Actually, as refined sugar is a toxin, and Americans consume ever-increasing quantities of it, perhaps some people ARE allowed to become both fat and alive by using antibiotics.
Posted by: Michael Herdegen at February 20, 2004 8:48 AM