IT'S ALL IN YOUR HEAD:

As vaccines rolled out across the country in 2021, researchers at the Mayo Clinic analyzed the symptoms of 108 patients who'd come for post-COVID care. Their results suggested that these patients fell into two main camps. Some, mostly men, suffered severe illness and were still being plagued by symptoms like chest pain and shortness of breath. Then there were others, mostly women, who had experienced relatively mild illness, or no symptoms at all, but were subsequently dogged by "widespread pain, fatigue," and "cognitive impairment, including the commonly reported "brain fog." The authors noted that this cluster of symptoms resembled a class of broadly similar conditions like chronic fatigue syndrome, fibromyalgia, and POTS (postural orthostatic tachycardia syndrome), all of which can leave sufferers incapacitated for years at a time. [...]

One study of patients in an Israeli health network looked at the incidence of 70 commonly reported long COVID symptoms in 150,000 patients. The researchers found that patients who'd been infected were more likely than people in a control group to suffer for extended periods from certain symptoms, in particular loss of taste and smell, concentration and memory problems, difficulty breathing, weakness, hair loss, palpitations, and chest pain. But the difference between the infected and controls largely disappeared by the end of the first year, and to the extent that they remained, they affected a relatively small number of patients. For instance, 407 of the COVID patients reported having persistent concentration and memory problems at the end of the first year, while 276 of the controls also did. That meant that for every 10,000 people, only about 13 had cognitive difficulties that were attributable specifically to COVID.

The researchers had gone into the project expecting to find a large number of chronic COVID aftereffects. Instead, they concluded that there were actually very few. "As we analyzed the data," the lead authors told Stat in January, "we were surprised to find only a small number of symptoms that were related to COVID and remained for a year post infection and the low number of people affected by them."

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